The results of our study underlined that the prevalence estimates of overall psychosis (21.21%) were remarkably higher than the previous systematic review reports from western countries among the homeless (12.7%) [ 65 ]. ScienceDaily, 21 December 2020. "We were able to find significant, meaningful differences with a small control group," Walss-Bass said. Schizophrenia is a severe mental disorder associated with impairment in functioning. Recently published articles from Schizophrenia Research. (3) Letters to the Editors: 600-800 words, 10 references, 1 figure or table. The risk of schizophrenia increases if a person inherits specific variants in a gene related to “synaptic pruning”—the elimination of connections between neurons—according to a study from Harvard Medical School, the Broad Institute and Boston Children’s Hospital. Seek schizophrenia support from a drop-in center . Effective treatments are available, yet patients and their families often find it hard to access good care. Copyright © 2020 Elsevier B.V. Real-world digital implementation of the Psychosis Polyrisk Score (PPS): A pilot feasibility study, Language as a biomarker for psychosis: A natural language processing approach, Cognitive dysfunction in a psychotropic medication-naïve, clinical high-risk sample from the ShangHai-At-Risk-for-Psychosis (SHARP) study: Associations with clinical outcomes, P300 as an index of transition to psychosis and of remission: Data from a clinical high risk for psychosis study and review of literature, Meta-analysis of cytokine and C-reactive protein levels in high-risk psychosis, Evidence of reward system dysfunction in youth at clinical high-risk for psychosis from two event-related fMRI paradigms, Modeling perception and behavior in individuals at clinical high risk for psychosis: Support for the predictive processing framework, Relationships between cognitive event-related brain potential measures in patients at clinical high risk for psychosis. No other disorder arouses as much anxiety in the general public, the media, and doctors. Those alterations are linked to whether a person has a higher risk of developing schizophrenia. Journals; Publish with us; Publishing partnerships; About us; Blog; Schizophrenia Research and Treatment + Journal Menu. Treatment is directed at ameliorating acute psychosis and reducing relapses. "We believe this has direct implications for the treatment of patients," said senior author Consuelo Walss-Bass, PhD, professor in the Louis A. Faillace, MD, Department of Psychiatry and Behavioral Sciences at McGovern Medical School at UTHealth. The signaling pathway researchers pinpointed is called phosphoinositide 3-kinase/glycogen synthase kinase 3 (PI3K/GSK3). This could help pinpoint who may respond better to treatments.". Anyone who wants to read the articles should pay by individual or institution to access the articles. Schizophrenia is a serious mental illness characterized by incoherent or illogical thoughts, bizarre behavior and speech, and delusions or hallucinations, such as hearing voices. Causes of Schizophrenia Research has not identified a singular cause of schizophrenia - it is thought to be a combination of genes and a range of environmental factors such as trauma, stress, problems at birth and significant drug use (WHO 2019; Reach Out 2020). Schizophrenia is a chronic, severe mental disorder that affects the way a person thinks, acts, expresses emotions, perceives reality, and relates to others. Effective … The journal publishes novel papers that really contribute to understanding the biology and treatment of schizophrenic disorders; Schizophrenia Research brings together biological, clinical and psychological research in order to stimulate the synthesis of findings from all disciplines involved in improving patient outcomes in schizophrenia. Browse health articles on schizophrenia treatments including anti-psychotic drugs. Or view hourly updated newsfeeds in your RSS reader: Keep up to date with the latest news from ScienceDaily via social networks: Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Through human-induced pluripotent stem cell (hiPSC) technology, the blood cells were reprogrammed into stem cells, which were then directed to become brain neurons. But not in psychiatric disorders. ... Convergent genomic and pharmacological evidence of PI3K/GSK3 signaling alterations in neurons from schizophrenia … For schizophrenia, a dose range of 37–148 mg daily is recommended, with a lower dose range of 18.5–120 mg daily, recommended for bipolar depression (lurasidone at lower doses of 20–60 mg daily has been shown to be as clinically efficacious in bipolar depression, as at the higher dose range of 80–100 mg/day). Since multiple factors may contribute, scientists cannot yet be specific about the exact cause in individual cases. The work being done by "Decode Genetics, Inc." in particular seems to be some of the most forward looking and progressive. Researchers believe that a number of genetic and environmental factors contribute to causation, and life stressors may play a role in the disorders onset and course. DSM-5 Diagnostic Criteria for Schizophrenia Two or more of the following must be present for at least one month or longer. The research was published in a recent issue of Neuropsychopharmacology. The schizophrenia research impact factor as of 2018 by Clarivative Analysis is 4.569. What You Can Do. Treatment of Adolescent and Child Schizophrenia Schizophrenia is much less common in children Read more... Posted by Megan at 09:24 PM | Comments (0) September 30, 2005 . Not so with schizophrenia, but neither has any conclusive research that I’ve seen shown evidence in either direction for it,but i digress. (6) Editorials. Schizophrenia Research. Adapted from the Encyclopedia of Psychology. Schizophrenia Articles Schizophrenia is one of the most serious and frightening of all mental illnesses. While genetic factors seem to play a role (i.e. A major achievement of this group has been the establishment of the Australian Schizophrenia Research Bank (ASRB) which collects biomedical samples and brain imaging data on schizophrenic and healthy patients to improve the sample size of research studies and allow easier detection of patterns and trends in patient samples. List of articles on schizophrenia; definition, causes, treatment of schizophrenia; information on schizoaffective disorder. Views expressed here do not necessarily reflect those of ScienceDaily, its staff, its contributors, or its partners. The Diagnostic and Statistical Manual IV-TRestablishes the clinical criteria for schizophrenia, with the foremost information concerning Criterion A . This research may help to understand how or why some antipsychotics targeting GSK3 work and also to develop other target-specific medications.". Yet research has consistently failed to directly link parenting to the onset of schizophrenia, although numerous investigations suggest that intense familial criticism may hasten … PLUS: Download citation style files for your favorite reference manager. Read current medical research on schizophrenia symptoms, medication and more. Original written by Deborah Mann Lake. “Convergent genomic and pharmacological evidence of PI3K/GSK3 signaling alterations in neurons from schizophrenia … The precise mechanism whereby raloxifene enhances cognition is not clear. In this report, the historical concepts of what constitutes the “characteristic symptoms” of schizophrenia are reviewed in the context of the development of DSM-IV. Researchers find link between tobacco cigarettes and depression and schizophrenia Published: 5 Nov 2019 Smoking may increase risk of mental health problems – study It is not intended to provide medical or other professional advice. In 2008 the National Institutes of Health established the Research, Condition and Disease Categorization Database (RCDC) that reports the amount spent by NIH institutes for each disease. The aim of the study was to understand treatment outcomes informal carers perceive to be important to people with schizophrenia. ScienceDaily. Using human-induced pluripotent stem cells engineered from a single family's blood samples, a gene signaling pathway linked to a higher risk for developing schizophrenia was discovered by scientists at The University of Texas Health Science Center at Houston (UTHealth). A lot of research has attempted to uncover the causes of schizophrenia. Schizophrenia Research and Treatment-Special Issue; Volume 2018 - Article ID 9898654 - Research Article; History of Suicide Attempt Is Associated with Reduced Medial Prefrontal Cortex Activity during Emotional Decision-Making among Men with Schizophrenia… Special Issues. Mini Antibodies Against COVID-19 from a Llama, Climate Change: Threshold for Dangerous Warming, River Civilizations' End: Climate Not Invasion, Exosome Treatment Improves Recovery from Heart Attacks in a Preclinical Study, Improving the Neuron Factory: New Modulator of Stem Cell Identity Found, Hidden Genetic Mutations in Stem Cells Could Undermine Therapeutic Benefit, Diet Modifications -- Including More Wine and Cheese -- May Help Reduce Cognitive Decline, Study Suggests, An Avocado a Day Keeps Your Gut Microbes Happy, Study Shows, Challenges of Fusing Robotics and Neuroscience, High-Five or Thumbs-Up? Note: Content may be edited for style and length. Relationship between allostatic load and clinical outcomes in youth at ultra-high risk for psychosis in the NEURAPRO study, Progressive reconfiguration of resting-state brain networks as psychosis develops: Preliminary results from the North American Prodrome Longitudinal Study (NAPLS) consortium, Thalamus-related anomalies as candidate mechanism-based biomarkers for psychosis, Immuno-inflammatory changes across phases of early psychosis: The impact of antipsychotic medication and stage of illness, Reprint of: Internalising symptoms mediate the longitudinal association between childhood inflammation and psychotic-like experiences in adulthood, Grey-matter abnormalities in clinical high-risk participants for psychosis, Guest Editorial: Special issue on “Biomarkers in the attenuated psychosis syndrome”, Risk of withdrawal of consent for treatment with long-acting injectable versus oral antipsychotics: A meta-analysis of randomized controlled trials, Echo of reading - The forgotten psychopathology: A case report, Psychotic experiences in seven-year-old children with familial high risk of schizophrenia or bipolar disorder in: The Danish High Risk and Resilience Study – VIA 7; A population-based cohort study, A new 3-hit mouse model of schizophrenia built on genetic, early and late factors, Embracing heterogeneity creates new opportunities for understanding and treating those at clinical-high risk for psychosis, Associations between duration of untreated psychosis and domains of positive and negative symptoms persist after 10 years of follow-up: A secondary analysis from the OPUS trial, Self-concept and Engagement in LiFe (SELF): A waitlist-controlled pilot study of a novel psychological intervention to target illness engulfment in enduring schizophrenia and related psychoses, Sequential Multiple-Assignment Randomized Trials to Compare Antipsychotic Treatments (SMART-CAT) in first-episode schizophrenia patients: Rationale and trial design, Adaptability and cohesion in youth at clinical high-risk for psychosis: A multi-informant approach, Psychosocial interventions for people with schizophrenia or psychosis on minimal or no antipsychotic medication: A systematic review, The long-term antipsychotic treatment of schizophrenia: A selective review of clinical guidelines and clinical case examples, Perspective on medication decisions following remission from first-episode psychosis, You say “schizophrenia” and I say “psychosis”: Just tell me when I can come off this medication, Relapse rates following antipsychotic discontinuation in the maintenance phase after first-episode of schizophrenia: Results of a long-term follow-up study, Rethinking the risks and benefits of long-term maintenance in schizophrenia, The influence of risk factors on the onset and outcome of psychosis: What we learned from the GAP study, Guest editorial: Special issue on maintenance treatment in schizophrenia, Definitions of relapse in trials comparing antipsychotic maintenance with discontinuation or reduction for schizophrenia spectrum disorders: A systematic review, Predictors of psychosis breakthrough during 24 months of long-acting antipsychotic maintenance treatment in first episode schizophrenia, Reprint of: Negative symptoms predict high relapse rates and both predict less favorable functional outcome in first episode psychosis, independent of treatment strategy, Amygdala connectivity during emotional face perception in psychotic disorders, Diagnostic uncertainty, antipsychotic dosing, and optimal psychosocial interventions: Unanswered questions in first-episode psychosis. 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