Our impartial buyers guide lets you know what to look out for to get the best products. View abstract. AIDS, arthritis, balancing intestinal flora, bone pain, bowel disorders, bursitis, cancer, candida, chronic fatigue syndrome, chronic pain, colitis, Crohn's disease, digestive complaints, duodenal ulcers, fungal infections, gastric ulcers, gastritis, gout, herpes, immune system deficiencies, improving DNA repair, inflammatory problems, intestinal complaints, irritable bowel syndrome, kidney cleanser, leaky bowel syndrome, osteoarthritis, parasites, stimulating the immune system, stomach problems, viral infections, urinary tract inflammation, wounds. 9-1-2011;137(1):856-863. Ccahuana-Vasquez, R. A., Santos, S. S., Koga-Ito, C. Y., and Jorge, A. O. Antimicrobial activity of Uncaria tomentosa against oral human pathogens. Symptoms:The most common include sneezing, nasal discharge and congestion, watery eyes, fever, and fatigueall of which can last up to two weeks. Systemic photosensitivity due to Goji berries. There are 34 reported species of Uncaria.U. Taking cat's claw along with medications for high blood pressure might cause your blood pressure to go too low. View abstract. View abstract. View abstract. Cats Claw is a vine commonly known as Una de Gato and is used traditionally in Peruvian medicine for the treatment of a wide range of health problems, particularly digestive complaints and arthritis and to treat wounds, stomach problems, cancer, and more. View abstract. Allen-Hall, L., Arnason, J. T., Cano, P., and Lafrenie, R. M. Uncaria tomentosa acts as a potent TNF-alpha inhibitor through NF-kappaB. Z Naturforsch.[C.] J Rheumatol 2002;29:678-81. View abstract. Instead of tetracyclic. View abstract. Most cancers and tumors are caused by viruses such as EBV. View abstract. View abstract. 2000;69(2):115-126. View abstract. Senatore, A., Cataldo, A., Iaccarino, F. P., and Elberti, M. G. [Phytochemical and biological study of Uncaria tomentosa]. 1999;5(2):143-151. [Pharmacological studies of indole alkaloids obtained from domestic plants, Uncaria rhynchophylla Miq. View abstract. Biology of Reproduction 1998;58(suppl 1):136. 2004;11(2-3):213-223. You are taking drugs that are substrates of Cytochrome P450 3A4, CYP2J2, UGT1A3, UGT1A9, ABCB1, and SLCO1B1, and PXR: Cat’s claw can … Georgian.Med.News 2009;(169):32-35. Chem.Pharm.Bull. The genus Uncaria is found mainly in tropical regions of Southeast Asia, the Asian continent, and South America. Int.Immunopharmacol. Garcia, Gimenez D., Garcia, Prado E., Saenz, Rodriguez T., Fernandez, Arche A., and De la Puerta, R. Cytotoxic effect of the pentacyclic oxindole alkaloid mitraphylline isolated from Uncaria tomentosa bark on human Ewing's sarcoma and breast cancer cell lines. Perez C, Calvo F, Silicani A, and et al. Hilepo, J. N., Bellucci, A. G., and Mossey, R. T. Acute renal failure caused by 'cat's claw' herbal remedy in a patient with systemic lupus erythematosus. Robertson, Sally. It’s also a potent anti-inflammatory agent and can be used to help heal inflammation-related conditions. View abstract. Phytochemistry 2005;66(1):89-98. The Journal Of Rheumatology found that pentacyclic oxindole alkaloids in … Diarrhea may occur when taken in high doses. Ozaki, Y. Lima, Peru 1997. This herb's anti-inflammatory properties may help to relieve arthritis, gout, and other inflammatory problems. Mimaki, Y., Toshimizu, N., Yamada, K., and Sashida, Y. Braz.Dent.J. Today, mainly by word of mouth, it has become one of the best selling herbs in the USA. Cat’s claw – Native to … Information from this source is evidence-based and objective, and without commercial influence. BMC.Complement Altern Med 2001;1:11. South Americans made use of it to ease conditions, such as fevers, arthritis, stomach ulcers, dysentery and inflammation. All rights reserved. Feline Infectious Peritonitis (FIP) This is one of the slow acting feline virus diseases. Knowing how to use or prepare herbs and what dosage to take is vital, to ensure safe and effective use. Pilarski, R., Filip, B., Wietrzyk, J., Kuras, M., and Gulewicz, K. Anticancer activity of the Uncaria tomentosa (Willd.) 1991;54(2):453-459. Herbs can be taken internally or used externally in various ways. In addition, the presence of glycosides, proanthocyanidins and beta sitosterol help provide anti-viral and anti-inflammatory support for the body. WebMD does not provide medical advice, diagnosis or treatment. Skin rash 4. DC mod. Mohamed AF, Matsumoto K, Tabata K, et al. Some medications are changed and broken down by the liver. De Paula LCL, Fonseca F, Perazzo F, et al. 1994;54(26):2061-2069. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.© Therapeutic Research Faculty . enhance immunity by stimulating the immune system. View abstract. This has led to its use as a adjunctive treatment for cancer and AIDS as well as other diseases that negatively impact the immunological system. The following doses have been studied in scientific research: Cancer. Olive Leaf. (check all that apply), What factors are most important to you? reduce pain and inflammation of rheumatism, arthritis and other types of inflammatory problems. View abstract. Are there safety concerns? View abstract. Uncaria tomentosa (cat's claw) improves quality of life in patients with advanced solid tumors. De Martino, L., Martinot, J. L., Franceschelli, S., Leone, A., Pizza, C., and De, Feo, V. Proapoptotic effect of Uncaria tomentosa extracts. By increasing the immune system cat's claw might decrease the effectiveness of medications that decrease the immune system. Leon FR, Ortiz N, Antunez de Mayolo A, and et al. It is effective against viruses, retroviruses, bacteria, spirochetes, rickettsiae, chlamydiae, fungi, yeasts, molds, protozoa, helminths and other parasites. View abstract. Heitzman, M. E., Neto, C. C., Winiarz, E., Vaisberg, A. J., and Hammond, G. B. Ethnobotany, phytochemistry and pharmacology of Uncaria (Rubiaceae). Provides Arthritis Relief. View abstract. Plant Physiol 1998;117(2):593-598. J.Altern.Complement Med. Sandoval-Chacon, M., Thompson, J. H., Zhang, X. J., Liu, X., Mannick, E. E., Sadowska-Krowicka, H., Charbonnet, R. M., Clark, D. A., and Miller, M. J. Antiinflammatory actions of cat's claw: the role of NF-kappaB. Parvovirus. Not since quinine was discovered in the bark of a Peruvian tree during the seventeenth century had any other rainforest plant ever prompted worldwide attention. J Nat.Prod. Cat's claw is considered a remarkably potent inhibitor of TNF-alpha production. Colorectal Dis 2010;12:799-803. Phytomedicine 2000;7:137-43. These alkaloids also exert a beneficial effect on memory. Rheumatoid arthritis (RA). Phytomedicine. View abstract. Cat’s claw is generally considered safe and effective as a complement to chemotherapy .Pregnant women should avoid using cat’s claw because of the herb’s potential to cause abortion .When cat’s claw was used in combination with some HIV treatments like protease inhibitors (atazanavir, ritonavir, and saquinavir), it increased their toxicity .Common side effects include : 1. View abstract. View abstract. Cat's claw contains many types of plant chemicals that help reduce inflammation, such as tannins and sterols, and fight viruses, such as quinovic acid glycosides. View abstract. 2010;76(2):133-136. Paper presented at Symposium on Uncarias. J.Ethnopharmacol. Volders/Tirol 1996;Austria:20. Oxindole alkaloids have been found to stimulate the immune system. View abstract. 12-1-2010;17(14):1133-1139. Akesson, C., Lindgren, H., Pero, R. W., Leanderson, T., and Ivars, F. An extract of Uncaria tomentosa inhibiting cell division and NF-kappa B activity without inducing cell death. Nippon Yakurigaku Zasshi 1989;94(1):17-26. Photodermatol.Photoimmunol.Photomed. Semin.Arthritis Rheum 2005;34(6):773-784. When taken in combination with other RA medications for 24 weeks, cat's claw seems to reduce the number of painful and swollen joints. A sexually transmitted infection that can lead to genital warts or cancer (human papillomavirus or HPV). Cat's claw contains chemicals that might stimulate the immune system, kill cancer cells, and fight viruses. Pentacyclic oxindole alkaloids from Uncaria tomentosa induce human endothelial cells to release a lymphocyte-proliferation-regulating factor. Akesson, C., Lindgren, H., Pero, R. W., Leanderson, T., and Ivars, F. Quinic acid is a biologically active component of the Uncaria tomentosa extract C-Med 100(R). Styczynski J, Wysocki M. Alternative medicine remedies might stimulate viability of leukemic cells. Aquino, R., De Simone, F., Pizza, C., Conti, C., and Stein, M. L. Plant metabolites. Sheng, Y., Bryngelsson, C., and Pero, R. W. Enhanced DNA repair, immune function and reduced toxicity of C-MED-100, a novel aqueous extract from Uncaria tomentosa. BMC.Complement Altern.Med. It is these seven different alkaloids that are credited with having a variety of different medicinal and healing properties. Since the 1970s, studies and research have been carried out by scientists in Peru, Germany, Austria, England and other countries, to find out more about the powerful healing properties of Cat's Claw. 2006;11(2):128-150. This finding suggests that when used with a vaccine, cat’s claw confers additional protection against the pneumonia virus. The cat may have trouble breathing or may have a raspy sound to his meow. help fight both viral and fungal infections such as Herpes and Candida. View abstract. Lowers High Blood Pressure. The olive leaf has antiviral properties, giving it the ability to treat the common cold and … Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with CAT'S CLAW. Sheng Y, Pero RW, Wagner H. Treatment of chemotherapy-induced leukopenia in a rat model with aqueous extract from Uncaria tomentosa. Cat's claw preparations are made from the root and bark of the cat's claw … View abstract. Castaneda O, Leon G, Leon D, and et al. 2006;132(5):615-622. Frackowiak, T., Baczek, T., Roman, K., Zbikowska, B., Glensk, M., Fecka, I., and Cisowski, W. Binding of an oxindole alkaloid from Uncaria tomentosa to amyloid protein (Abeta1-40). ( FIP ) this is one of the species Uncaria guianensis infections, and South America Stein M.! 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